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Jaclyn Schwarz

Associate Professor
University of Delaware
110 Wolf Hall
Newark, DE 19716
302-831-4582
Lab Address: 096 McKinly Lab
Lab Phone: 302-831-7623
 

Biography

Dr. Jaclyn Schwarz received her PhD from the University of Maryland Medical School, where she examined the mechanisms by which testosterone masculinizes neural circuits in the neonatal brain. She continued her training as a postdoctoral fellow at Duke University, where she studied how early-life experiences, including parental care, can program the function of the immune system, and thereby affect later-life brain and behaviors.  In her own lab at the University of Delaware, she is currently funded by 3 NIH grants to study the neural-immune mechanisms by which early-life immune activation (both bacterial and viral) can disrupt the development of important neural circuits that control learning, and how these mechanisms and effects may be different between males and females.  She has been the recipient of the Frank Beach Young Investigator Award from the Society for Behavioral Neuroendocrinology, as well as a NARSAD Young Investigator Award from the Brain and Behavior Research Foundation.​

Degrees

B.A. Psychology Boston College
Ph.D. Neuroscience University of Maryland, School of Medicine

Courses Regularly Taught

PSYC/NSCI431 Hormones and Behavior

PSYC314 Brain and Behavior

NSCI430/630 Integrative Neuroscience II​

Recent Publications

Dr. Schwarz's Google Scholar Link

Schwarz JM, Smith SH, Bilbo SD. FACS analysis of neuronal-glial interactions in the nucleus accumbens following morphine administration. Psychopharmacology (2013) Dec; 230(4):  525-35.

Schwarz JM and Bilbo SD.  Adolescent morphine exposure increases the risk of relapse to drug-seeking behavior in adulthood:  critical role for long-term changes in glial function.  Journal of Neuroscience (2013) Jan 16; 33(3):961-71.

Schwarz JM*, Sholar PS*, Bilbo SD.  Sex differences in microglial colonization of the developing rat brain. Journal of Neurochemistry (2012) Mar; 120(6):948-63. 

* Both authors contributed equally to this work.

Schwarz JM, Hutchinson MR, Bilbo SD.  Early-Life Experience Decreases Potential Abuse Liability of Morphine in Adulthood via Microglial-Specific Epigenetic Programming of Anti-Inflammatory IL-10 Expression. Journal of Neuroscience (2011) 31(49):17835-17847

Schwarz JM and Bilbo SD.  LPS elicits a much larger and broader inflammatory response than Escherichia coli infection within the hippocampus of neonatal rats. Neurosci. Lett. (2011) Jun 22; 497(2):  110-5.

​Terasaki LS and Schwarz JM. Effect of Low Dose Prenatal Alcohol Exposure during Early Gestation on Inflammation in the Maternal-Fetal-Immune Interface and Later-Life Immune Function in the Offspring, Journal of Neuroimmune Pharmacology, (IN PRESS).

Brenhouse HC and Schwarz JM. Adolescence and the Immune System: Impact on Alcohol Use and Abuse. Neurosci and Biobehav Rev 2016 epub ahead of print.

Tannenbaum C, Schwarz JM, Clayton JA, de Vries GJ, and Sullivan C. Evaluating sex as a biological variable in preclinical research: The devil is in the details. A commentary. Biology of Sex Differences 2016; 7:13. 

Terasaki LS, Gomez, J, and Schwarz JM. An Examination of Sex Differences in the Effects of Early-Life Opiate and Alcohol Exposure. Philosophical Transactions B 2016; 371(1688): 20150123.

Posillico CK and Schwarz JM. An investigation into the effects of antental stress on the postpartum neuroimmune profile and depressive-like behaviors. (2016) Behavioral Brain Research Feb 1, 298 (Pt B): 218-28.

Posillico CK, Terasaki LS, Bilbo SD, Schwarz JM. Effects of Sex on Morphine-Induced Analgesia and Inflammatory Gene Expression along the Pain Pathway in Male and Female Sprague Dawley Rats. (2015) Biology of Sex Differences Dec 12;6: 33.

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