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Tania Roth

Associate Dean for the Natural Sciences
Professor of Psychological and Brain Sciences
University of Delaware
Newark, DE 19716
 

Biography

Dr. Roth received her Bachelor of Science degree in Biology from Roanoke College in 1998. She then completed her doctoral degree in 2004 in the laboratory of Dr. Regina Sullivan at the University of Oklahoma, where she investigated the neurobehavioral basis of infant-caregiver attachment and the ontogeny of fear learning and memory. She then did her postdoctoral research at the University of Alabama at Birmingham in the laboratory of David Sweatt, working on DNA methylation in CNS plasticity and behavior. In 2010 she joined the University of Delaware as an Assistant Professor of Psychological and Brain Sciences. Dr. Roth has received numerous honors and awards for scholarship, including a Young Investigator Award from the Brain & Behavior Research Foundation, the 2010 Ziskind-Somerfeld award from the Society of Biological Psychiatry, a 2015 Early Career Impact Award from the Federation of Associations in Behavioral & Brain Sciences, and she was elected a Kavli Fellow of the National Academy of Sciences in 2012. She is currently funded by the NIH, and her primary research interests are centered on identifying epigenetic changes associated with early-life caregiving experiences, particularly maltreatment. To better understand the relationship between caregiver maltreatment, epigenetic marking of the genome, and behavioral outcomes, her laboratory utilizes various molecular and behavior assays in developing and adult male and female rats. They focus on multiple brain regions that play a significant role in behavior and mental health, and that are particularly susceptible to the damaging effects of early-life stress.

Degrees

Ph.D., University of Oklahoma

Courses Regularly Taught

PSYC428: Nature vs. Nurture- Genetic and Environmental Determinants of Behavior

NSCI634: Stress and the Brain

NSCI637: Behavioral Epigenetics

Representative Publications

A Asok, K Bernard, JB Rosen, M Dozier, TL Roth. 2014. Infant-caregiver experiences alter telomere length in the brain. PLOS One 9:e101437.

J Blaze, L Scheuing, TL Roth. 2013. Differential methylation of genes in the medial prefrontal cortex of developing and adult rats following exposure to maltreatment or nurturing care during infancy. Developmental Neuroscience 35:306-316.

TL Roth, PR Zoladz, JD Sweatt, DM Diamond. 2011. Epigenetic modification of hippocampal BDNF DNA in adult rats in an animal model of post-traumatic stress disorder. Journal of Psychiatric Research 45:919-926.

TL Roth, FD Lubin, AJ Funk, and JD Sweatt. 2009. Lasting epigenetic influence of early-life adversity on the BDNF gene. Biological Psychiatry 65:760-769.

TL Roth and RM Sullivan. 2005. Memory of maltreatment: Neonatal behavioral and neural correlates of maternal maltreatment within the context of classical conditioning. Biological Psychiatry 57:823-831.

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