
Tania Roth
Associate Dean for the Natural Sciences
Professor of Psychological and Brain Sciences
University of Delaware
Newark, DE 19716
Biography
Dr.
Roth received her Bachelor of Science degree in Biology from Roanoke College
in 1998. She then completed her
doctoral degree in 2004 in the laboratory of Dr. Regina Sullivan at the
University of Oklahoma, where she investigated the neurobehavioral basis of
infant-caregiver attachment and the ontogeny of fear learning and
memory. She then did her postdoctoral
research at the University of Alabama at Birmingham in the laboratory of
David Sweatt, working on DNA methylation in CNS plasticity and behavior. In 2010 she joined the University of
Delaware as an Assistant Professor of Psychological and Brain Sciences. Dr. Roth has received numerous honors and
awards for scholarship, including a Young Investigator Award from the Brain
& Behavior Research Foundation, the 2010 Ziskind-Somerfeld award from the
Society of Biological Psychiatry, a 2015 Early Career Impact Award from the
Federation of Associations in Behavioral & Brain Sciences, and she was
elected a Kavli Fellow of the National Academy of Sciences in 2012. She is currently funded by the NIH, and her
primary research interests are centered on identifying epigenetic changes
associated with early-life caregiving experiences, particularly
maltreatment. To better understand the
relationship between caregiver maltreatment, epigenetic marking of the
genome, and behavioral outcomes, her laboratory utilizes various molecular
and behavior assays in developing and adult male and female rats. They focus on multiple brain regions that
play a significant role in behavior and mental health, and that are
particularly susceptible to the damaging effects of early-life stress.
Degrees
Ph.D., University
of Oklahoma
Courses Regularly Taught
PSYC428:
Nature vs. Nurture- Genetic and Environmental Determinants of Behavior
NSCI634: Stress and the Brain
NSCI637: Behavioral Epigenetics
Representative Publications
A Asok,
K Bernard, JB Rosen, M Dozier, TL Roth. 2014. Infant-caregiver experiences
alter telomere length in the brain. PLOS One 9:e101437.
J Blaze, L Scheuing, TL Roth. 2013. Differential methylation of genes in
the medial prefrontal cortex of developing and adult rats following exposure
to maltreatment or nurturing care during infancy. Developmental Neuroscience
35:306-316.
TL Roth, PR Zoladz, JD Sweatt, DM Diamond. 2011. Epigenetic modification of
hippocampal BDNF DNA in adult rats in an animal model of post-traumatic
stress disorder. Journal of Psychiatric Research 45:919-926.
TL Roth, FD Lubin, AJ Funk, and JD Sweatt. 2009. Lasting epigenetic
influence of early-life adversity on the BDNF gene. Biological Psychiatry 65:760-769.
TL Roth and RM Sullivan. 2005. Memory of maltreatment: Neonatal behavioral and neural correlates
of maternal maltreatment within the context of classical conditioning.
Biological Psychiatry 57:823-831.
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