Behavioral Neuroscience

Kevin Brown

		Graduate Student  -  Primary Advisor: Mark Stanton Research Interests Recent Publications   brownkev@udel.edu Office: 126B Wolf Hall (302) 831-0647 (302) 831-0687 -fax Preferred contact method - email

Research Interests

Learning and Behavior; Developmental Toxicology

Research Summary:

I am interested in studying the development of learning and memory using the rodent eyeblink preparation.  Specifically, I plan to examine the contribution of the cerebellar cortex in the development of timing and amplitude of the rat eyeblink response.  Other work I have done includes early exposure of ethanol to neonatal rats as part of a rodent model of fetal alcohol syndrome.  Since exposure to ethanol at specific developmental periods can cause a dose-dependent cell loss in the cerebellum and eyeblink conditioning taps an identified brainstem-cerebellar circuit, the eyeblink preparation is an ideal model to examine the behavioral effects of early ethanol exposure.  Additionally I have worked on spatial learning in developing rats.

Recent Publications

Brown, K.L., Calizo, L.H., & Stanton, ME. (2008). Dose-dependent deficits in dual interstimulus interval classical eyeblink conditioning tasks following neonatal binge alcohol exposure in rats. Alcoholism: Clinical and Experimental Research, 32, 277-293.

Brown, K.L., Calizo, L.H., Goodlett, C.R., & Stanton, M.E. (2007). Neonatal alcohol exposure impairs acquisition of eyeblink conditioned responses during discrimination learning and reversal in weanling rats. Developmental Psychobiology, 49, 243-257.

Stanton, M.E., Peloso, E., Brown, K.L., & Rodier, P. (2007). Discrimination learning and reversal of the conditioned eyeblink reflex in a rodent model of autism. Behavioural Brain Research, 176, 133-140.

Brown, K.L., Pagani, J.H, & Stanton, M.E. (2006). The ontogeny of interstimulus interval (ISI) discrimination of the conditioned eyeblink response in rats. Behavioral Neuroscience, 120, 1057-1070.

Brown, K.L., Pagani, J.H., & Stanton, M.E. (2005). Spatial conditional discrimination learning in the juvenile rat. Developmental Psychobiology, 46, 97-110.

Pagani, J.H., Brown, K.L., & Stanton, M.E. (2005). Contextual modulation of spatial discrimination reversal in developing rats. Developmental Psychobiology, 46, 36-46.

Page, M.E., Brown, K., & Lucki, I. (2003). Simultaneous analyses of the neurochemical and behavioral effects of the norepinephrine reuptake inhibitor reboxetine in a rat model of antidepressant action. Psychopharmacology (Berl), 165, 194-201.

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