Mark E. Stanton
Developmental psychobiology of learning and memory
Dr. Stanton is interested in the developmental psychobiology of learning and memory and its applications to developmental neurobehavioral disorders. His current research focuses on the developmental analysis of eyeblink conditioning from a multiple memory systems perspective in rodents and humans. Eyeblink conditioning offers the opportunity to (a) analyze the ontogeny of associative learning in relation to a well-characterized brainstem-cerebellar circuit; (b) study cognitive and affective development in relation to interactions with this circuit of forebrain structures such as the hippocampus, amygdala, and prefrontal cortex; and (c) better compare these aspects of memory development in humans and animal models. Abnormal development of the cerebellum and hippocampus is implicated in a number of neurobehavioral disorders. Dr. Stanton and his colleagues are using eyeblink conditioning to better understand the etiology and developmental determinants of disorders such as autism, fetal alcohol syndrome, and other environmental or genetic conditions.
Herbert, J.H., Eckerman, C.O., & Stanton, M.E. The ontogeny of human learning in delay, long-delay, and trace eyeblink conditioning. Behavioral Neuroscience, 2003, 117, 1196-1210
Claflin, D., Stanton, M.E. , Herbert, J.S., Greer, J., Eckerman, C.O. Effect of delay interval on classical eyeblink conditioning in 5-month-old human infants. Developmental Psychobiology, 2002, 41, 329-340.
Ivkovich, D. & Stanton, M.E. Effects of hippocampal lesions on trace, delay, and long-delay eyeblink conditioning in developing rats. Neurobiology of Learning and Memory, accepted (2001).
Rush, A.N., Robinette, B.L., & Stanton, M.E. Ontogenetic differences in the effects of unpaired stimulus preexposure on eyeblink conditioning in the rat. Developmental Psychobiology, 2001, 39, 8-18.
Stanton, M.E. Multiple memory systems, development, and conditioning. Behavioral Brain Research, 2000, 110, 25-37.
Stanton, M.E. & Freeman, J.H. Developmental studies of eyeblink conditioning in the rat. In D.S. Woodruff-Pak and J.E. Steinmetz (Eds.) Eyeblink classical conditioning, Volume II: Animal models. Amsterdam: Kluwer Academic Publishers, 2000 (pp. 105-134).
Ivkovich, D., Eckerman, C.O., Krasnegor, N.A., & Stanton, M.E. Using eyeblink conditioning to assess neurocognitive development. In D.S. Woodruff-Pak and J.E. Steinmetz (Eds.) Eyeblink classical conditioning, Volume I: Applications in Humans. Amsterdam: Kluwer Academic Publishers, 2000 (pp. 119-142).
Paczkowski, C. M., Ivkovich, D. & Stanton, M.E. Ontogeny of eyeblink conditioning using a visual conditional stimulus. Developmental Psychobiology, 1999, 35, 253-263.